Manganese is the forming element of some enzymes participating in animals' metabolism of carbohydrate, lipid and protein. When lack of manganese, their skeletons are misshapen, animals will grow slow, enginery is abnormal and newborns will be ataxic. Manganese is also an anticipant in forming of skeleton.

MnSO4. H2O: Mn¡Ý31.8, Pb¡Ü0.001, As¡Ü0.0005